Protein Molecular Weight Markers
ABclonal Technology SRPRB Rabbit pAb
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
ABclonal Technology CACNG1 Rabbit pAb
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
ABclonal Technology SEC11A Rabbit pAb
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
ABclonal Technology CDC34 Rabbit mAb
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
ABclonal Technology HAS1 Rabbit pAb
Hyaluronan (HA) is a high molecular weight polysaccharide found in the extracellular matrix, composed of alternating glucuronic acid and N-acetylglucosamine linked by β-1,3 and β-1,4 bonds. Synthesized by membrane-bound synthases, HA is extruded into the extracellular space and plays roles in joint lubrication, space filling, and supporting cell migration. It is actively produced during wound healing and tissue repair and is involved in leukocyte homing via interaction with CD44. HA levels are altered in conditions like rheumatoid arthritis, and overexpression of HA receptors is linked to tumor metastasis. HAS1 encodes a hyaluronan synthase and shares homology with similar genes in other species. Alternative splicing produces multiple transcript variants.
ABclonal Technology ADIPOR1 Rabbit pAb
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
ABclonal Technology Adenosine Deaminase (ADA) Rabbit pAb
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine in the purine catabolic pathway. Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined immunodeficiency disease (SCID) which is the result of a deficiency in the ADA enzyme. In ADA-deficient individuals there is a marked depletion of T, B, and NK lymphocytes, and consequently, a lack of both humoral and cellular immunity. Conversely, elevated levels of this enzyme are associated with congenital hemolytic anemia.
ABclonal Technology SERPINA9 Rabbit pAb
Enables serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in cytoplasm and membrane. Predicted to be active in extracellular space.
ABclonal Technology NUDT6 Rabbit pAb
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology METTL21C Rabbit pAb
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in protein methylation. Located in nucleus. Part of protein-containing complex.
ACROBiosystems Star Ribbon Pre-stained Protein Marker (40-275 kDa)
This product is a mixture of seven highly purified pre-stained proteins ranging from 40 kDa to 275 kDa. The 275 kDa and 72 kDa bands are orange, 50 kDa band is green, and other bands are blue. It is designed for observing protein separation during SDS-PAGE, verifying western transfer efficiency on membranes, and approximating the size of proteins.
Sigma Aldrich Fine Chemicals Biosciences Gel filtration Markers Kit
Gel filtration markers kit contains five vials of proteins and 1 vial of blue dextran for calibration.
ABclonal Technology ZCCHC10 Rabbit pAb
Predicted to enable nucleic acid binding activity and zinc ion binding activity.
ABclonal Technology MTM1 Rabbit pAb
This gene encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy.